Longitudinal evaluation of CA-125 velocity and prediction of ovarian cancer
نویسندگان
چکیده
منابع مشابه
Longitudinal evaluation of CA-125 velocity and prediction of ovarian cancer.
OBJECTIVE To determine whether CA-125 velocity is a statistically significant predictor of ovarian cancer and develop a classification rule to screen for ovarian cancer. METHODS In the ovarian component of the PLCO cancer screening trial, 28,038 women aged 55-74 had at least two CA-125 screening tests. Ovarian cancer was diagnosed in 72 (0.26%) women. A multiple logistic regression model was ...
متن کاملSerum CA 125 and ovarian cancer
of death from gynaecological cancer among women in Western countries. Epithelial ovarian cancer is responsible for 85-90% of all primary ovarian tumours. Because of the asymptomatic nature of the disease, ovarian cancer is usually not detected in the early stages and therefore many women present with advanced disease and systemic metastases. Approximately 70-80% of patients present with late st...
متن کاملCA 125 in ovarian cancer: advances and controversy.
Ovarian cancer continues to be a major health threat for women. The American Cancer Society estimates that in the United States in 1998, 25 400 new cases will be diagnosed and 14 500 women will die as a result of this disease (1). Most of these cancers are epithelial in origin, as germ cell tumors of the ovary represent only ;5% of the total. Approximately 70% of epithelial ovarian cancers will...
متن کاملLevel and evaluation of tumor marker CA-125 in ovarian cancer patients in Khyber Pakhtunkhwa, Pakistan.
BACKGROUND Due to the increase in morbidity and mortality rate, cancer has become an alarming threat to the human population worldwide. Since cancer is a progressive disorder, timely diagnosis is necessary to prevent/stop cancer from progressing to a severe stage. In Khyber Paktunkhwa, Pakistan, many tumors are diagnosed with endoscopy and biopsy; rare studies exist regarding the diagnosis and ...
متن کاملA longitudinal analysis with CA-125 to predict overall survival in patients with ovarian cancer
OBJECTIVE The objective of this study was to explore the association of longitudinal CA-125 measurements with overall survival (OS) time by developing a flexible model for patient-specific CA-125 profiles, and to provide a simple and reliable prediction of OS. METHODS A retrospective study was performed on 275 patients with ovarian cancer who underwent at least one cycle of primary chemothera...
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ژورنال
عنوان ژورنال: Gynecologic Oncology
سال: 2012
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2011.12.440